On a typical weekday there are 16 scheduled rail journeys between Milton Keynes Central and Glasgow Central, with 3 of them being direct trains. There are also a further 13 possible journeys which require a change.

The distance by rail from Milton Keynes Central to Glasgow Central is approximately 300 miles (482 kilometres). The average train journey takes about 5hrs 42 mins.

Avanti West Coast and Caledonian Sleeper and West Midlands Trains and First TransPennine Express are the main train operating companies running services between Milton Keynes Central and Glasgow Central.

There are 7 possible routes with the shortest and most direct being Milton Keynes Central to Glasgow Central. The fastest journey time on this route takes 4hrs 17 mins.